Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: cchoe@uke.de. Epidemiological Study Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Department of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Department of Vascular Medicine, University Heart and Vascular Center, Hamburg, Germany; German Center of Cardiovascular Research (DZHK); Partner Site Hamburg/Lübeck/Kiel, Hamburg, Germany. German Center of Cardiovascular Research (DZHK); Partner Site Hamburg/Lübeck/Kiel, Hamburg, Germany; Department of General and Interventional Cardiology, University Heart and Vascular Center, Hamburg, Germany. German Center of Cardiovascular Research (DZHK); Partner Site Hamburg/Lübeck/Kiel, Hamburg, Germany; Institute of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.